Urinary tract infections during pregnancy – clinical picture and therapeutic approach in the Infectious Diseases Hospital of Iaşi (2009-2012)

Results The annual number of the admissions was relatively constant, except for the year 2010 with 25 cases; the infections were more frequent in 26-40 years old pregnant women (63.3%), during the first (38.3%) and the second trimester of pregnancy (48.3%) and in primiparous women (61.7%). Fever was present in 71.7% of the patients, 51.7% having also digestive symptomatology. The inflammatory syndrome was illustrated at admission through leukocytosis (in 66.7% cases), high values of ESR (88.9% cases), and of fibrinogen (31% of cases). Pyuria was present in 75% of cases, and in 25.7% were associated albuminuria. 65% cases were considered lower urinary tract infections. The etiology was established in 73.3% cases, being dominated by E coli (88.3%); also implicated were: Klebsiella spp. (6.7%), Streptococcus spp. (1.7%), Candida 3.3%. The etiologic treatment was based on beta-lactams, especially in association with beta-lactamase inhibitors: amoxicillin-clavulanate – 43.3%, ampicillin-sulbactam – 3.3%, second generation cephalosporins – 16.7% or third generation cephalosporins (18.3%) and carbapenems – 10%. The evolution was favorable in all the cases, with no immediate negative effects on the baby.